Rather than directly harm a user, some Gadgets have the side-effect of slowly transforming them into something else.
This is a variation on the Infection Alien Trait. If the character uses the Gadget without wearing some form of protection, then the Gadget transforms the character.
As a Minor Bad Trait, the Gadget gives the character the equivalent of Alien Appearance (patches of skin turn to stone, the character grows an extra eye).
As a Major Bad Trait, then the character actually becomes a member of an alien species as per the Infection trait.